Olfactory sensitivity in CD-1 mice for the sperm-attractant odorant bourgeonal and some of its structural analogues
Independent thesis Advanced level (degree of Master (Two Years)), 40 credits / 60 HE creditsStudent thesis
Using a conditioning paradigm and an automated olfactometer, I investigated the olfactory sensitivity of five CD-1 mice for seven aromatic aldehydes. With two of the stimuli (3-phenylpropanal and canthoxal), the animals discriminated concentrations as low as 10 ppb (parts per billion) from the odorless solvent and with four of the stimuli (helional, cyclamal, lilial and lyral) they discriminated concentrations as low as 1 ppb, with single individuals even scoring better. All five animals yielded the by far lowest threshold value with bourgeonal and discriminated a concentration of 0.1 ppq (parts per quadrillion) from the odorless solvent. The detection threshold values for aromatic aldehydes were found to be affected by the type of functional groups and oxygen moiety attached to the benzene ring. A comparison of the present data with those obtained in other species found no clear correlation between olfactory sensitivity and the size of the olfactory receptor repertoire.
Place, publisher, year, edition, pages
2010. , 21 p.
Aromatic aldehydes, CD-1 mice, olfactory detection thresholds
IdentifiersURN: urn:nbn:se:liu:diva-56813ISRN: LiTH-IFM-A-Ex-10/2352-SEOAI: oai:DiVA.org:liu-56813DiVA: diva2:322286
2010-05-28, Linköpings universitet, 15:31 (English)
UppsokLife Earth Science
Laska, Matthias, Professor
Amundin, Mats, adj. professor