TRP channels and regulation of blood flow in the brood patch of Zebra finches (Taeniopygia guttata)
Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
During the breeding season Zebra finch, Taeniopygia guttata, females develops a brood patch on the ventral surface which facilitates heat exchange between the incubating bird and the egg. The brood patch has to be sensitive to changes in temperature, so that the eggs can be kept at an optimal temperature for embryo development. If the egg temperature drops it has to be re-warmed. Mild cooling of the brood patch has been shown to cause cold induced vasodilation, but the responsible mechanism for this is not known. In this study we investigated if known thermoreceptors, TRPV3 and TRPV4, could be involved in the alteration of blood flow. To activate TRPV3 and TRPV4 two agonists, carvacrol and 4α-PDD respectively, were applied on the brood patch. Changes in skin temperature and vascularity were then examined. The results obtained did not reveal any changes in the vascularity. Temperature changes in the skin that could be caused by an alteration in blood flow did not significantly change either. Still, a role of these channels in the brood patch cannot be excluded.
Place, publisher, year, edition, pages
2010. , 18 p.
4α-PDD, Brood patch, Carvacrol, TRPV3, TRPV4, Zebra finch
IdentifiersURN: urn:nbn:se:liu:diva-58148ISRN: LITH-IFM-G-EX--10/2339—SEOAI: oai:DiVA.org:liu-58148DiVA: diva2:332365
Altimiras, Jordi, Docent
Anders, Hargeby, Lektor