liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
PTFE Bypass to Below-knee Arteries: Distal Vein Collar or Not? A Prospective Randomised Multicentre Study
Linköping University, Department of Medicine and Health Sciences, Physiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart Centre, Department of Cardiology.
Show others and affiliations
2010 (English)In: European Journal of Vascular and Endovascular Surgery, ISSN 1078-5884, E-ISSN 1532-2165, Vol. 39, no 6, 747-754 p.Article in journal (Refereed) Published
Abstract [en]

Background: Patency and limb salvage after synthetic bypass to the arteries below-knee are inferior to that which can be achieved with autologous vein. Use of a vein collar at the distal anastomosis has been suggested to improve patency and limb salvage, a problem that is analysed in this randomised clinical study. Methods: Patients with critical limb ischaennia undergoing polytetrafluoroethylene (PTFE) bypass to below-knee arteries were randomly either assigned a vein collar or not in two groups bypass to the popliteal artery below-knee (femoro-popliteal below-knee (FemPopBK)) and more distal bypass (femoro-distal bypass (FemDist)). Follow-up was scheduled until amputation, death or at most 5 years, whichever event occurred first. Results: In the FemPopBK and in the FemDist groups, 115/202 and 72/150 were randomised to have a vein collar, respectively. Information was available for 345 of 352 randomised patients (98%). At 3 years, primary patency was 26% (95% confidence interval (CI) 18-38) with a vein collar and 43 (33-58) without a vein collar for femoro-popliteal bypass and 20 (11-38), and 17 (9-33) for femoro-distal bypass, respectively. The corresponding figures for limb salvage were 64 (54-75) and 61(50-74) for femoro-popliteal bypass, and 59 (46-76) and 44 (32-61) for femoro-distal bypass with and without a vein collar, respectively. Log-rank-test for the whole Kaplan-Meier life table curve showed no statistically significant differences with or without vein collar primary patency: p = 0.0853, p = 0.228; secondary patency: p = 0.317, p = 0.280; limb salvage: p = 0.757, p = 0.187 for FemPopBK and FemDist, respectively. The use of a vein collar did not influence patency or limb salvage. Conclusion: This study failed to show any benefit for vein collar with PTFE bypass to a below-knee artery.

Place, publisher, year, edition, pages
Elsevier Science B.V., Amsterdam , 2010. Vol. 39, no 6, 747-754 p.
Keyword [en]
PTFE bypass; Femoro-popliteal; Femoro-crural; Popliteal arteries; Tibial arteries; Vein collar; Critical limb ischaemia
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-58235DOI: 10.1016/j.ejvs.2010.01.016ISI: 000279522700017OAI: diva2:338037
Available from: 2010-08-10 Created: 2010-08-09 Last updated: 2011-03-08

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Lundgren, FredrikJönsson, Björn
By organisation
PhysiologyFaculty of Health SciencesDepartment of CardiologyDepartment of Thoracic and Vascular Surgery
In the same journal
European Journal of Vascular and Endovascular Surgery
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 15546 hits
ReferencesLink to record
Permanent link

Direct link