Temporal 3D Lagrangian strain from 2D slice followed cine DENSE MRI
2012 (English)In: Clinical Physiology and Functional Imaging, ISSN 1475-0961, E-ISSN 1475-097X, Vol. 32, no 2, 139-144 p.Article in journal (Refereed) Published
A quantitative analysis of myocardial mechanics is fundamental to the understanding of cardiac function, diagnosis of heart disease and assessment of therapeutic intervention. In the clinical situation, where limited scan time often is important, a detailed analysis of the myocardium in a specific region might be more applicable than a full 3D measurement of the entire left ventricle. This paper presents a method to obtain temporal evolutions of transmural 3D Lagrangian strains from two intersecting 2D planes of slice followed cine displacement encoding with stimulated echoes (DENSE) data using a bilinear-cubic polynomial element to resolve strain from the displaced myocardial positions. The method demonstrates accurate results when validated in an analytical model, and has been applied to in vivo data acquired on a 3 T magnetic resonance (MR) system from a healthy volunteer to quantify systolic strains at the anterior-basal region of left ventricular myocardium. The in vivo results agree within experimental accuracy with values reported in the literature.
Place, publisher, year, edition, pages
Wiley-Blackwell, 2012. Vol. 32, no 2, 139-144 p.
Myocardium; kinematics; magnetic resonance; transmural
Engineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-60200DOI: 10.1111/j.1475-097X.2011.01068.xISI: 000299734400010OAI: oai:DiVA.org:liu-60200DiVA: diva2:355635