liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Non-invasive monitoring of blood haemoglobin for analysis of fluid volume kinetics
Linköping University, Department of Medical and Health Sciences, Anesthesiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Anaesthetics, Operations and Specialty Surgery Center, Department of Anaesthesiology and Surgery.
Linköping University, Department of Medical and Health Sciences, Anesthesiology. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Medical and Health Sciences, Anesthesiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Anaesthetics, Operations and Specialty Surgery Center, Department of Hand and Plastic Surgery. Östergötlands Läns Landsting, Anaesthetics, Operations and Specialty Surgery Center, Department of Anaesthesiology and Surgery.
2010 (English)In: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 54, no 10, 1233-1240 p.Article in journal (Refereed) Published
Abstract [en]

Background: A commercially available pulse oximeter that reports blood haemoglobin (Hb) concentration is evaluated. This study considers whether this device can provide serial Hb data that would be sufficiently reliable for volume kinetic analysis of infusion fluids.

Methods: Forty infusions of 5 or 10 ml/kg of acetated Ringer's solution were given over 15 min in 10 healthy volunteers. Hb was measured on 17 different occasions over 120 min using the Radical 7 pulse oximeter and compared with the result of invasive blood sampling (control). A one-volume kinetic model was applied to each data series. The pulse oximeter also reported the perfusion index (PI).

Results: The median deviation between the 680 invasive and non-invasive Hb samples (the accuracy) was 1.6% and the absolute median deviation (precision) was 4.6%. Between-subject factors explained half of the variation in the difference between non-invasive vs. invasive sampling.

Ten of the 40 non-invasive series of Hb values were discarded from kinetic analysis due to poor quality. The remaining 30 series showed a smaller distribution volume for the infused fluid when kinetic analysis was based on the non-invasive method (3.0 vs. 5.3 l; P<0.001). This was due to co-variance with the PI, which exaggerated the decrease in Hb caused by the infusions. The non-invasive method might provide useful kinetic data at the group level, but individual curves deviated too much from the invasive data to be reliable.

Conclusions: Non-invasive measurement of the Hb concentration during volume loading could not provide useful kinetic data for individuals.

Place, publisher, year, edition, pages
Blackwell Publishing Ltd , 2010. Vol. 54, no 10, 1233-1240 p.
National Category
Anesthesiology and Intensive Care
Identifiers
URN: urn:nbn:se:liu:diva-60717DOI: 10.1111/j.1399-6576.2010.02321.xISI: 000282687400011PubMedID: 21039345Scopus ID: 2-s2.0-78650205631OAI: oai:DiVA.org:liu-60717DiVA: diva2:359783
Available from: 2010-10-29 Created: 2010-10-22 Last updated: 2017-12-12Bibliographically approved

Open Access in DiVA

fulltext(645 kB)136 downloads
File information
File name FULLTEXT02.pdfFile size 645 kBChecksum SHA-512
0310ded544f73ba6d182b81f9ca93cd17d2a41b6c167a69f416b02acb6207d6f36c413bd5ae8688fd5fd0535fb569465762727964a44a15a403a1d6a357c31f7
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records BETA

Hahn, RobertZdolsek, Joachim

Search in DiVA

By author/editor
Hahn, RobertZdolsek, Joachim
By organisation
AnesthesiologyFaculty of Health SciencesDepartment of Anaesthesiology and SurgeryDepartment of Hand and Plastic Surgery
In the same journal
Acta Anaesthesiologica Scandinavica
Anesthesiology and Intensive Care

Search outside of DiVA

GoogleGoogle Scholar
Total: 687 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 121 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf