Transient Anterior Corneal Deposits in a Human Immunodeficiency Virus-Positive Patient
2010 (English)In: CORNEA, ISSN 0277-3740, Vol. 29, no 11, 1323-1327 p.Article in journal (Refereed) Published
Purpose: To report findings of pigmented anterior corneal deposits in a human immunodeficiency virus-positive patient. Methods: Case report. A 49-year-old human immunodeficiency virus-positive patient was examined after the appearance of pigmented corneal deposits. Slit-lamp biomicroscopy, fundus photography, and laser-scanning in vivo confocal microscopy were performed to visually document the ocular condition. Results: The patient had a history of Mycobacterium avium infection and was suspected to have recovery uveitis from a cytomegalovirus infection. Small, rounded, light brown-colored deposits were distributed across the anterior cornea from limbus to limbus, bilaterally. In vivo confocal microscopy revealed the deposits to be confined to the basal epithelium and Bowman layer, whereas the posterior stroma, Descemet membrane, and the endothelium appeared normal. Systemic steroid treatment was administered, and 2 weeks later, the deposits had vanished on slit-lamp examination, whereas remnants were observed at the microscopic level. Conclusions: The deposits were unusual for their anterior corneal location and pancorneal distribution. The response to systemic steroid treatment remains unexplained and illustrates the complexity of the underlying conditions, their treatment, and the associated pathways of ocular manifestation.
Place, publisher, year, edition, pages
Lippincott Williams and Wilkins , 2010. Vol. 29, no 11, 1323-1327 p.
cytomegalovirus, HIV, Mycobacterium avium, corneal deposit, Bowman layer
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-61203DOI: 10.1097/ICO.0b013e3181d07670ISI: 000283329800023OAI: oai:DiVA.org:liu-61203DiVA: diva2:360873
Beatrice Bourghardt Peebo, Per Fagerholm and Neil Lagali, Transient Anterior Corneal Deposits in a Human Immunodeficiency Virus-Positive Patient, 2010, CORNEA, (29), 11, 1323-1327.
Copyright: Lippincott Williams & Wilkins