HDR imaging evaluation of a NT-proBNP test with a mobile phone.
2011 (English)In: Biosensors & bioelectronics, ISSN 0956-5663, E-ISSN 1873-4235, Vol. 26, no 5, 2107-2113 p.Article in journal (Refereed) Published
The determination of NT-proBNP levels is key for the monitoring of patients with diagnosed heart failure and it is a routine measurement typically performed at health care centers, which would benefit from decentralized alternatives. Here we investigate the quantitative evaluation of a well-established NT-proBNP test using a standard mobile phone (Nokia 6720) as measuring platform rather than a dedicated instrument. A Java ME software developed for this application controls the illumination and imaging of the proBNP test under defined time intervals, which enables the composition of multi-exposure sets that are processed as high dynamic range (HDR) images for contrast enhancement. The results show that HDR processing significantly increases the sensitivity and resolution of the technique achieving a performance within the diagnostics range. These results demonstrate the feasibility to exploit a ubiquitous device to decentralize the evaluation of a routine test and identify key processing alternatives to bring the performance of such systems within the diagnostics range.
Place, publisher, year, edition, pages
2011. Vol. 26, no 5, 2107-2113 p.
IdentifiersURN: urn:nbn:se:liu:diva-63708DOI: 10.1016/j.bios.2010.09.015ISI: 000286904400051PubMedID: 20926279OAI: oai:DiVA.org:liu-63708DiVA: diva2:382348