liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Differentiated thyroid cancer in a Swedish county--long-term results and quality of life.
Ryhov Hospital.
Ryhov Hospital.
Ryhov Hospital.
Ryhov Hospital.
Show others and affiliations
2010 (English)In: Acta Oncologica, ISSN 0284-186X, E-ISSN 1651-226X, Vol. 49, no 4, 454-459 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: There is still no complete agreement about the proper treatment of differentiated thyroid cancer (DTC).

MATERIAL AND METHODS: All patients (n=130) with DTC in a defined population, treated with surgery between 1985 and 1999, were carefully followed up (median 13.1 years). Fifty three were operated with subtotal and 77 with total thyroidectomy. Twenty seven percent of the patients in the subtotal group and 56% of those in the total thyroidectomy group had postoperative radioiodine ablation. Thirty nine patients had papillary cancers incidentally detected during surgery for benign disorders (median size 7 (1-30) mm). Living patients answered the Swedish version of the SF-36 health survey.

RESULTS: Eleven of 106 patients considered tumour-free after primary surgery developed recurrences during follow-up. Fifteen patients (12%) died from DTC but only one within stage I-II (1.2%). No patient below 50 years of age at diagnosis died from DTC. Only three of 29 patients with isolated loco-regional spreading of their disease at the time of diagnosis have died from thyroid cancer. There was no statistically significant difference in the 10 year cancer-specific survival rate between those operated with subtotal or total thyroidectomy--irrespective of stage. Survival rate was significantly better for papillary than for follicular cancer. Mental and physical quality of life among patients treated for DTC were similar to the healthy Swedish population.

CONCLUSIONS: Patients with DTC stage I-II (according to TNM) or low-risk (according to AMES) have an excellent prognosis. Treatment as well as follow-up should not be exaggerated.

Place, publisher, year, edition, pages
2010. Vol. 49, no 4, 454-459 p.
URN: urn:nbn:se:liu:diva-64276OAI: diva2:388679
Available from: 2011-01-18 Created: 2011-01-18 Last updated: 2011-02-13

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Andersson, Roland EJärhult, J
In the same journal
Acta Oncologica

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 23 hits
ReferencesLink to record
Permanent link

Direct link