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Geometric risk factors for atherosclerosis in the aortic bifurcation: a digitized angiography study.
Department of Diagnostic Radiology, Uppsala University.ORCID iD: 0000-0002-7750-1917
1996 (English)In: Annals of Biomedical Engineering, ISSN 0090-6964, E-ISSN 1573-9686, Vol. 24, no 4, 481-488 p.Article in journal (Refereed) Published
Abstract [en]

To clarify the relationship between arterial geometry and atherosclerosis at the aortic bifurcation, angiograms of 84 patients with slight or moderate atherosclerosis were studied by computerized image analysis. The degree of atherosclerosis involvement was assessed as angiographic edge roughness. The branching angles were found to be related to edge roughness of the left outer wall and the right side of the aorta. The position of the flow divider was related to edge roughness of the medial wall of the right common iliac and the right side of the aorta. For these two locations, there were also significant relationships to the area ratio, i.e., the ratio between cross-sectional areas distal and proximal to the bifurcations. On the basis of these findings, the concept of "geometric risk factors" for atherosclerosis and the potential influence of blood flow on atherogenesis are discussed.

Place, publisher, year, edition, pages
1996. Vol. 24, no 4, 481-488 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-63988DOI: 10.1007/BF02648110PubMedID: 8841723OAI: diva2:390239
Available from: 2011-01-21 Created: 2011-01-10 Last updated: 2013-09-05

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Smedby, Örjan
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ReferencesLink to record
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