Evaluation of Portwine Stain Perfusion by Laser Doppler Imaging and Thermography Before and After Argon Laser Treatment
1992 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, Vol. 72, no 1, 6-10 p.Article in journal (Refereed) Published
Thirteen patients with port wine stains (PWS) were treated with argon laser therapy. Before and at different points in time following treatment, skin blood perfusion and temperature were mapped with laser Doppler imaging and thermography. In nine patients no elevation in blood perfusion was observed in the PWS in comparison with the surrounding normal skin before treatment. In the remaining four patients a significantly (p less than 0.01) higher blood flow was recorded within the PWS. Immediately after treatment nine patients showed elevated perfusion within the PWS. During the first two days following treatment, all patients showed a gradually decreasing hyperperfusion in the borderline between the PWS lesion and surrounding skin. Immediately after treatment 10 patients had a significantly (p less than 0.01) higher temperature in the PWS than in normal skin. During the first 24 h following treatment, an elevated perfusion was in general accompanied by a tissue temperature increase. Three and a half months after argon laser treatment, three patients showed excellent clinical results with no remaining PWS spots or scarring. Two of these patients had had both elevated perfusion and temperature in the PWS prior to treatment.
Place, publisher, year, edition, pages
1992. Vol. 72, no 1, 6-10 p.
Medical Laboratory and Measurements Technologies
IdentifiersURN: urn:nbn:se:liu:diva-64697OAI: oai:DiVA.org:liu-64697DiVA: diva2:394156