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Amperometric tetrathiafulvalene-mediated lactate electrode using lactate oxidase absorbed on carbon foil
Cranfield Institute of Technology, Biotechnology Centre, Cranfield, Bedford , UK.
Cranfield University, UK.ORCID iD: 0000-0002-1815-9699
1990 (English)In: Analytica Chimica Acta, ISSN 0003-2670, E-ISSN 1873-4324, Vol. 234, no 2, 459-463 p.Article in journal, Letter (Other academic) Published
Abstract [en]

The features of a new sensor for determining l-lactate are reported. The enzyme lactate oxidase and the mediator, tetrathiafulvalene (TTF), are absorbed on carbon foil disks previously bonded onto the ends of glass tubes. Linear calibration graphs were obtained in the range 10−4−10−3 M with physiological phosphate buffer (pH 7.35) and at 30°C with a response time of a few seconds. Calibration graphs in the range 10−3−10−2 M were also obtained and the difference in response times between these two ranges were investigated. The results are promising for assembling disposable lactate sensors for in vitro or for in or ex vivo measurements.

Place, publisher, year, edition, pages
Elsevier, 1990. Vol. 234, no 2, 459-463 p.
Keyword [en]
Lactate, Enzyme electrode, Tetrathiafulvalene mediator
National Category
Natural Sciences
URN: urn:nbn:se:liu:diva-65311DOI: 10.1016/S0003-2670(00)83591-6ISI: A1990DT58800023OAI: diva2:394921
Available from: 2011-02-04 Created: 2011-02-04 Last updated: 2013-10-04

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Turner, Anthony P. F.
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ReferencesLink to record
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