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In vitro diagnostics in diabetes: Meeting the challenge
Cranfield University, UK.ORCID iD: 0000-0002-1815-9699
Cranfield University, Institute Biosci and Technology, Cranfield MK43 0AL, Beds, England; .
Cranfield University, Institute Biosci and Technology, Cranfield MK43 0AL, Beds, England; .
1999 (English)In: Clinical Chemistry, ISSN 0009-9147, E-ISSN 1530-8561, Vol. 45, no 9, 1596-1601 p.Article in journal (Refereed) Published
Abstract [en]

Diabetes is one of the leading causes of death and disability in the world. There is a large population in the world suffering from this disease, and the healthcare costs increase every year. It is a chronic disorder resulting from insulin deficiency and hyperglycemia and has a high risk of development of complications for the eyes, kidneys, peripheral nerves, heart, and blood vessels. Quick diagnosis and early prevention are critical for the control of the disease status. Traditional biosensors such as glucose meters and glycohemoglobin test kits are widely used in vitro for this purpose because they are the two major indicators directly involved in diabetes diagnosis and long-term management. The market size and huge demand for these tests make it a model disease to develop new approaches to biosensors. In this review, we briefly summarize the principles of biosensors, the current commercial devices available for glucose and glycohemoglobin measurements, and the recent work in the area of artificial receptors and the potential for the development of new devices for diabetes specifically connected with in vitro monitoring of glucose and glycohemoglobin HbA(1c). (C) 1999 American Association for Clinical Chemistry.

Place, publisher, year, edition, pages
American Association for Clinical Chemistry; 1999 , 1999. Vol. 45, no 9, 1596-1601 p.
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-65242ISI: 000082382100040OAI: diva2:394993
Available from: 2011-02-04 Created: 2011-02-04 Last updated: 2013-10-04

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