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Organic bioelectronics in nanomedicine
Karolinska Institute.
Karolinska Institute.
Linköping University, Department of Science and Technology, Physics and Electronics. Linköping University, The Institute of Technology.ORCID iD: 0000-0003-4791-4785
Karolinska Institute.
2011 (English)In: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, ISSN 0304-4165, Vol. 1810, no 3, 276-285 p.Article, review/survey (Refereed) Published
Abstract [en]

Background: Nanomedicine is a research area with potential to shape, direct, and change future medical treatments in a revolutionary manner over the next decades. While the common goal with other fields of biomedicine is to solve medical problems, this area embraces an increasing number of technology platforms as they become miniaturized. Organic electronics has over the past two decades developed into an exciting and thriving area of research. Scope of review: Today, the organic electronics field stands at the interface with biology. As the area of organic bioelectronics advances, it holds promise to make major contributions to nanomedicine. The progress made in this direction is the topic of this review. Major conclusions: We describe the inherent features of conducting polymers, and explain the usefulness of these materials as active scaffolds in cell biology and tissue engineering. We also explain how the combined ionic and electronic conductive nature of the polymers is used to precisely control the delivery of signal substances. This unique feature is key in novel devices for chemical communication with cells and tissues. General significance: This review highlights the results from the creative melting pot of interdisciplinary research in organic bioelectronics. This article is part of a Special Issue entitled Nanotechnologies - Emerging Applications in Biomedicine.

Place, publisher, year, edition, pages
ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS , 2011. Vol. 1810, no 3, 276-285 p.
Keyword [en]
Organic bioelectronics, Tissue engineering, Drug delivery, Ca2+ signalling, Spatial-temporal gradients
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-66148DOI: 10.1016/j.bbagen.2010.10.001ISI: 000287470900006OAI: diva2:401909
Available from: 2011-03-04 Created: 2011-03-04 Last updated: 2015-05-06

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