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Requirements and Design of the PROSPER Protocol for Implementation of Information Infrastructures Supporting Pandemic Response: A Nominal Group Study
Linköping University, Department of Medical and Health Sciences, Division of Preventive and Social Medicine and Public Health Science. Linköping University, Faculty of Health Sciences.ORCID iD: 0000-0001-6049-5402
Linköping University, Department of Computer and Information Science, MDALAB - Human Computer Interfaces. Linköping University, The Institute of Technology.
ANSER Analyt Serv Inc.
Umea University.
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2011 (English)In: PLOS ONE, ISSN 1932-6203, Vol. 6, no 3, 0017941- p.Article in journal (Refereed) Published
Abstract [en]

Background: Advanced technical systems and analytic methods promise to provide policy makers with information to help them recognize the consequences of alternative courses of action during pandemics. Evaluations still show that response programs are insufficiently supported by information systems. This paper sets out to derive a protocol for implementation of integrated information infrastructures supporting regional and local pandemic response programs at the stage(s) when the outbreak no longer can be contained at its source. Methods: Nominal group methods for reaching consensus on complex problems were used to transform requirements data obtained from international experts into an implementation protocol. The analysis was performed in a cyclical process in which the experts first individually provided input to working documents and then discussed them in conferences calls. Argument-based representation in design patterns was used to define the protocol at technical, system, and pandemic evidence levels. Results: The Protocol for a Standardized information infrastructure for Pandemic and Emerging infectious disease Response (PROSPER) outlines the implementation of information infrastructure aligned with pandemic response programs. The protocol covers analyses of the community at risk, the response processes, and response impacts. For each of these, the protocol outlines the implementation of a supporting information infrastructure in hierarchical patterns ranging from technical components and system functions to pandemic evidence production. Conclusions: The PROSPER protocol provides guidelines for implementation of an information infrastructure for pandemic response programs both in settings where sophisticated health information systems already are used and in developing communities where there is limited access to financial and technical resources. The protocol is based on a generic health service model and its functions are adjusted for community-level analyses of outbreak detection and progress, and response program effectiveness. Scientifically grounded reporting principles need to be established for interpretation of information derived from outbreak detection algorithms and predictive modeling.

Place, publisher, year, edition, pages
Public Library of Science (PLoS) , 2011. Vol. 6, no 3, 0017941- p.
National Category
Social Sciences
URN: urn:nbn:se:liu:diva-67828DOI: 10.1371/journal.pone.0017941ISI: 000289053800006OAI: diva2:413603
Original Publication: Toomas Timpka, Henrik Eriksson, Elin A Gursky, Magnus Stromgren, Einar Holm, Joakim Ekberg, Olle Eriksson, Anders Grimvall, Lars Valter and James M Nyce, Requirements and Design of the PROSPER Protocol for Implementation of Information Infrastructures Supporting Pandemic Response: A Nominal Group Study, 2011, PLOS ONE, (6), 3, 0017941. Copyright: Public Library of Science (PLoS) Available from: 2011-04-29 Created: 2011-04-29 Last updated: 2013-09-05

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Timpka, ToomasEriksson, HenrikEkberg, JoakimEriksson, OlleGrimvall, AndersValter, Lars
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Division of Preventive and Social Medicine and Public Health ScienceFaculty of Health SciencesMDALAB - Human Computer InterfacesThe Institute of TechnologyStatisticsFaculty of Arts and SciencesCentre for Public Health
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