Health-related quality of life is impaired in active collagenous colitis
2011 (English)In: DIGESTIVE AND LIVER DISEASE, ISSN 1590-8658, Vol. 43, no 2, 102-109 p.Article in journal (Refereed) Published
Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL survey, 116 patients with collagenous colitis at four Swedish hospitals completed four health-related quality of life questionnaires, two disease-specific (Inflammatory Bowel Disease Questionnaire and Rating Form of IBD Patient Concerns), and two generic (Short Form 36, SF-36, and Psychological General Well-Being, PGWB), and a one-week symptom diary. Demographic and disease-related data were collected. Results for the collagenous colitis population were compared with a background population controlled for age and gender (n = 8931). Results: Compared with a Swedish background population, patients with collagenous colitis scored significantly worse in all Short Form 36 dimensions (p andlt; 0.01), except physical function. Patients with active disease scored worse health-related quality of life than patients in remission. Co-existing disease had an impact on health-related quality of life measured with the generic measures. Lower education level and shorter disease duration were associated with decreased well-being. Conclusion: Health-related quality of life was impaired in patients with collagenous colitis compared with a background population. Disease activity is the most important factor associated with impairment of health-related quality of life. Patients in remission have a health-related quality of life similar to a background population.
Place, publisher, year, edition, pages
Elsevier Science B.V., Amsterdam , 2011. Vol. 43, no 2, 102-109 p.
Collagenous colitis, Health, Health-related quality of life, Inflammatory bowel disease (IBD), Microscopic colitis, Quality of life
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-68229DOI: 10.1016/j.dld.2010.06.004ISI: 000290008100004OAI: oai:DiVA.org:liu-68229DiVA: diva2:416852