Modified surfaces using tailor-made oligosaccharides having orthogonal attachments
2011 (English)In: Abstract of Papers of the American Chemical Society, ISSN 0065-7727, Vol. 241, 107-CARB- p.Article in journal, Meeting abstract (Other academic) Published
The ability of fabricating surfaces with low non-specific protein adhesion is of great interest in material science. Studies have shown that self-assembled monolayers (SAMs) covered with carbohydrates moieties have protein resistant characteristics and even marine anti-fouling properties.[1,2]The presented results describe the synthesis of oligosaccharides originating from lactose and mannose. We have also set out to investigate if these orthogonally protected oligosaccharides can be used as spacer molecules and their performance in protein adsorption studies. Using the selected divergence enables incorporation into various surface systems e.g. gold nanoparticles, vesicles or as a conjugate between different macromolecules.
 Hederos, M.; Konradsson, P.; Liedberg, B.; Langmuir, 2005, 21, 2971-2980. Fyrner, T.; Konradsson, P.; et. al.; Submitted, 2010.
Place, publisher, year, edition, pages
American Chemical Society (ACS), 2011. Vol. 241, 107-CARB- p.
Engineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-69923ISI: 000291982802352OAI: oai:DiVA.org:liu-69923DiVA: diva2:433186
241st ACS National Meeting & Exposition, Anaheim, California, USA, March 27-31 2011,