Randomized trial of Internet-based relapse prevention for partially remitted depression
2011 (English)In: Acta Psychiatrica Scandinavica, ISSN 0001-690X, E-ISSN 1600-0447, Vol. 124, no 4, 285-294 p.Article in journal (Refereed) Published
Objective: To investigate whether Internet-based cognitive behaviour therapy (CBT) can prevent relapse in persons with partially remitted major depression after previous treatment. less thanbrgreater than less thanbrgreater thanMethod: Seventy-one women and 13 men (N = 84) with partially remitted major depression after treatment were randomly assigned to either 10 weeks of Internet-based CBT or to a control group. Self-help material was used in combination with e-mail contact with a personal therapist. Monthly self-ratings of depressive symptoms were made, and diagnostic interviews were conducted before and after the treatment period, as well as 6 months later. less thanbrgreater than less thanbrgreater thanResults: Significantly fewer participants in the CBT group experienced relapse (4/38 or 10.5%) compared with those in the control group (14/37 or 37.8%). The difference in relapse rates between groups occurred early in the study period and was still apparent after 6 months. A trend towards a larger reduction in depressive symptoms was observed at post-treatment in the participants who received CBT compared with controls. Reduction in depressive symptoms reduced the risk of relapse. A trend towards a higher remission rate was found in the CBT group at the 6 month follow-up. less thanbrgreater than less thanbrgreater thanConclusion: Internet-based CBT seems promising in preventing relapse in persons with partially remitted major depression after previous treatment.
Place, publisher, year, edition, pages
John Wiley and Sons , 2011. Vol. 124, no 4, 285-294 p.
depression, recurrence, Internet, self-care, cognitive behaviour therapy
IdentifiersURN: urn:nbn:se:liu:diva-71072DOI: 10.1111/j.1600-0447.2011.01698.xISI: 000294872900006OAI: oai:DiVA.org:liu-71072DiVA: diva2:444868
Funding Agencies|Swedish Psychiatry Foundation (Psykiatrifonden)||Capio Research Foundation||National Association for Social and Mental Health (RSMH)||2011-09-302011-09-302014-11-28