Association of 25-Hydroxyvitamin D(3) Levels in Adult New Zealanders with Ethnicity, Skin Color and Self-Reported Skin Sensitivity to Sun Exposure
2011 (English)In: Photochemistry and Photobiology, ISSN 0031-8655, E-ISSN 1751-1097, Vol. 87, no 5, 1173-1178 p.Article in journal (Refereed) Published
The study aim was to determine the contribution of ethnicity, objectively measured skin color and skin reaction-to-sun exposure to variations in 25-hydroxyvitamin D(3) [25(OH)D(3)]. A multiethnic sample (European, Maori, Pacific and Asian) of 503 adult volunteers aged 18-85 years, recruited from Auckland and Dunedin in New Zealand, answered a questionnaire on sun exposure and self-defined ethnicity. Skin color was measured using a spectrophotometer and the Individual Typology Angle (ITA) calculated. A blood sample was collected 4 weeks later to measure 25(OH)D(3). 25(OH)D(3) was associated with ethnicity, but not self-reported skin reaction-to-sun exposure. Amongst the ethnic groups, Asians had the lowest mean 25(OH)D level (37.0 nmol L(-1)) and Europeans with lighter colored skin had the highest (57.9 nmol L(-1)). An association also was seen between 25(OH)D(3) and skin color, with an increase of 2-3 nmol L(-1) per 10 degrees increase in ITA value, indicating higher 25(OH)D(3) with lighter skin color; but much of this association disappeared after adjusting for ethnicity. In contrast, ethnicity remained associated with 25(OH)D(3) after adjusting for ITA skin color and skin reaction-to-sun exposure. These results indicate that self-defined ethnicity was a major determinant of variations in serum 25(OH)D(3), while objective measures of skin color explained relatively little additional variation.
Place, publisher, year, edition, pages
Wiley-Blackwell , 2011. Vol. 87, no 5, 1173-1178 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-71223DOI: 10.1111/j.1751-1097.2011.00956.xISI: 000295049700028OAI: oai:DiVA.org:liu-71223DiVA: diva2:446345
Funding Agencies|Health Research Council of New Zealand||Cancer Society of New Zealand||University of Otago||2011-10-072011-10-072011-10-07