liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Effects of moderate red wine consumption on liver fat and blood lipids: a prospective randomized study
Linköping University, Department of Medical and Health Sciences, Internal Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Centre, Department of Endocrinology and Gastroenterology UHL.
Linköping University, Department of Medical and Health Sciences, Internal Medicine. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Medical and Health Sciences, Internal Medicine. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Medical and Health Sciences, Radiation Physics. Linköping University, Faculty of Health Sciences. Linköping University, Center for Medical Image Science and Visualization, CMIV.
Show others and affiliations
2011 (English)In: Annals of Medicine, ISSN 0785-3890, E-ISSN 1365-2060, Vol. 43, no 7, 545-554 p.Article in journal (Refereed) Published
Abstract [en]

Background : There have been no human prospective randomized studies of the amount of alcohol that can induce hepatic steatosis. less thanbrgreater than less thanbrgreater thanMethods : Thirty-two healthy women and twelve healthy men (34 +/- 9 years of age) were randomized to consume 150 ml of red wine/day for women (16 g ethanol/day) or double that amount for men (33 g ethanol/day), or to alcohol abstention for 90 days. Participants underwent proton-nuclear magnetic-resonance spectroscopy for measurement of hepatic triglyceride content (HTGC). Blood samples for assessment of cardiovascular risk were drawn before and after the intervention. less thanbrgreater than less thanbrgreater thanResults: After exclusion of three subjects with steatosis at baseline a trend towards increased HTGC was apparent for red wine (before median: 1.1%, range 0.2-3.9%, after median: 1.1%, range 0.5-5.2%, P = 0.059) a difference that was statistically significant compared with abstainers (p = 0.02). However, no subject developed hepatic steatosis. Low-density lipoprotein (LDL)-cholesterol was lowered by red wine (-0.3 mmol/l, SE-0.1, 95% CI-0.6 to -0.04). less thanbrgreater than less thanbrgreater thanConclusions: Moderate consumption of red wine during three months increased HTGC in subjects without steatosis at baseline. However, since not a single participant developed steatosis we suggest that the threshold of alcohol consumption to define nonalcoholic fatty liver disease should not be lower than the amount in our study.

Place, publisher, year, edition, pages
Informa Healthcare , 2011. Vol. 43, no 7, 545-554 p.
Keyword [en]
alcohol, hepatic triglyceride content, NAFLD
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-71373DOI: 10.3109/07853890.2011.588246ISI: 000295127900005OAI: oai:DiVA.org:liu-71373DiVA: diva2:448075
Note
|Available from: 2011-10-14 Created: 2011-10-14 Last updated: 2017-12-08

Open Access in DiVA

fulltext(302 kB)2390 downloads
File information
File name FULLTEXT01.pdfFile size 302 kBChecksum SHA-512
52fa536fa3b6698a752488839b2f83ac7a4cb54bc59d228c48a34822049c04068b4ed7382e3c5ccb3ffe64c6d118d48551c4e048d92ca61a287655a7e3eda977
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Authority records BETA

Kechagias, StergiosDahlqvist Leinhard, OlofKihlberg, JohanSmedby, ÖrjanLindström, TorbjörnNyström, Fredrik

Search in DiVA

By author/editor
Kechagias, StergiosDahlqvist Leinhard, OlofKihlberg, JohanSmedby, ÖrjanLindström, TorbjörnNyström, Fredrik
By organisation
Internal MedicineFaculty of Health SciencesDepartment of Endocrinology and Gastroenterology UHLRadiation PhysicsCenter for Medical Image Science and Visualization, CMIVRadiologyDepartment of Radiology in Linköping
In the same journal
Annals of Medicine
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 2390 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 488 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf