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Thrombotic microangiopathy
Umeå University.
Linköping University, Department of Clinical and Experimental Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Centre for Diagnostics, Department of Clinical Immunology and Transfusion Medicine.
University of Uppsala Hospital.
University Hospital, Örebro.
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2011 (English)In: Transfusion and apheresis science, ISSN 1473-0502, E-ISSN 1878-1683, Vol. 45, no 2, 119-123 p.Article in journal (Refereed) Published
Abstract [en]

Thrombotic microangiopathy (TMA) is a histopathological feature of various diseases including thrombotic thrombocytopenic purpura (UP) and hemolytic uremic syndrome (HUS). There are many secondary causes of TMA, many of them could mimic TTP or HUS. This article presents a short overview on TMA. In conclusion TMA is the result of various etiology reasons and pathologic reactions with various clinical entities. It is important to focus on a thorough history including family history when deciding on a diagnosis. Analysis of ADAMTS 13 and ADAMTS 13-antibodies may help to decide continued therapy.

Place, publisher, year, edition, pages
Elsevier , 2011. Vol. 45, no 2, 119-123 p.
Keyword [en]
Thrombotic microangiopathy, Hemolytic uremic syndrome, ADAMTS13, TMA, TTP, HUS
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-72266DOI: 10.1016/j.transci.2011.07.002ISI: 000296406200003OAI: diva2:458800
Available from: 2011-11-24 Created: 2011-11-24 Last updated: 2011-11-24

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Berlin, Gösta
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Department of Clinical and Experimental MedicineFaculty of Health SciencesDepartment of Clinical Immunology and Transfusion Medicine
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