liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Development of a harmonised method for the profiling of amphetamines: IV. Optimisation of sample preparation
Swedish National Laboratory of Forensic Science.
National Bureau of Investigation, Finland.
University of Lausanne.
Netherlands Forensic Institute.
Show others and affiliations
2007 (English)In: Forensic Science International, ISSN 0379-0738, E-ISSN 1872-6283, Vol. 169, no 1, 64-76 p.Article in journal (Refereed) Published
Abstract [en]

The suitability of liquid–liquid extraction (LLE) and solid-phase extraction (SPE) for the preparation of impurity extracts intended for gas chromatographic profiling analyses of amphetamine were evaluated. Both techniques were optimised with respect to the extraction of selected target compounds by use of full factorial designs in which the variables affecting the performance were evaluated. Test samples consisted of amphetamine synthesised by the Leuckart reaction, by reductive amination of benzyl methyl ketone and by the nitrostyrene route. The performance of LLE and SPE were comparable in terms of repeatability and recovery of the target compounds. LLE was considered the better choice for the present harmonised amphetamine profiling method due to the lack of information on the long-term stability of SPE columns.

Place, publisher, year, edition, pages
Elsevier , 2007. Vol. 169, no 1, 64-76 p.
Keyword [en]
Amphetamine; Impurities; Profiling; Optimisation; SPE; LLE; GC-FID; GC–MS
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:liu:diva-72289DOI: 10.1016/j.forsciint.2006.10.017ISI: 247113600008OAI: oai:DiVA.org:liu-72289DiVA: diva2:459014
Available from: 2011-11-24 Created: 2011-11-24 Last updated: 2017-12-08

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Dahlén, Johan

Search in DiVA

By author/editor
Dahlén, Johan
In the same journal
Forensic Science International
Engineering and Technology

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 40 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf