liu.seSearch for publications in DiVA
Change search
ReferencesLink to record
Permanent link

Direct link
Radiobiology of prostate cancer
Östergötlands Läns Landsting, Center for Surgery, Orthopaedics and Cancer Treatment, Department of Radiation Physics. Linköping University, Faculty of Health Sciences. Linköping University, Department of Medical and Health Sciences, Division of Radiological Sciences.ORCID iD: 0000-0001-8171-2541
2012 (English)In: Robotic Radiosurgery. Treating Prostate Cancer and Related Genitourinary Applications / [ed] Ponsky LE, Fuller DB, Meier RM, Ma C-MC, Springer Berlin/Heidelberg, 2012, 79-101 p.Chapter in book (Refereed)
Abstract [en]

The 1999 proposal of Brenner and Hall of an alpha/beta value of 1.5 Gy for prostate tumors has rekindled the interest in the traditional radiobiological aspects of time, dose, and fractionation as effective means of modulating the therapeutic window in radiation therapy. It is well established that, depending on the fractionation sensitivity of normal and tumor tissues, one could depart from the usual fractionation pattern and devise schedules that lead to the same tumor results with less complications, or better tumor control with the same level of complications. Nevertheless, radiobiology experience indicates that the success of any fractionation schedule depends on the temporal pattern of dose delivery. From this perspective, the present chapter aims to review the radiobiological aspects that may be relevant for the design of treatment schedules for prostate tumors.

Place, publisher, year, edition, pages
Springer Berlin/Heidelberg, 2012. 79-101 p.
National Category
Medical and Health Sciences Cancer and Oncology
URN: urn:nbn:se:liu:diva-72634DOI: 10.1007/978-3-642-11495-3_8ISBN: 978-3642114946OAI: diva2:460926
Available from: 2011-12-01 Created: 2011-12-01 Last updated: 2015-05-07

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Dasu, Alexandru
By organisation
Department of Radiation PhysicsFaculty of Health SciencesDivision of Radiological Sciences
Medical and Health SciencesCancer and Oncology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 387 hits
ReferencesLink to record
Permanent link

Direct link