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Sleep-wake-activity rhythm and health-related quality of life among patients with coronary artery disease and in a population-based sample –an actigraphy and questionnaire study
Linköping University, Department of Medical and Health Sciences. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Sinnescentrum, Department of Neurophysiology UHL.
Linköping University, Department of Medical and Health Sciences, Nursing Science. Linköping University, Faculty of Health Sciences.
(English)Manuscript (preprint) (Other academic)
Abstract [en]

The aim of this study was to explore whether there are gender differences in sleep and health related quality of life in patients with coronary artery disease CAD and a matched population-based sample and to see how subjectively rated sleep is associated with actigraphy. Secondly, whether factors that predict patients´ sleep quality could be identified. Fifty-seven patients with stable CAD and forty-seven participants from a population-based sample were included. All participants completed the Uppsala Sleep Inventory (USI), the Epworth Sleepiness Scale and the SF-36. Actigraphy recordings and a sleep diary were performed for 7 days. Multiple stepwise regression analysis showed that sleep duration, sleep onset latency, nocturnal awakenings, vitality (SF-36) and BMI explained 60% of the sleep quality outcome (USI) (P<0.0001). Sleep duration, sleep efficiency and fragmentation index assessed with actigraphy and sleep diary accounted for 36% of the sleep quality outcome (diary, P<0.0001). The result can form the basis for a non-pharmacological, self-care programme supported and led by nurses.

 

Keyword [en]
Actigraphy, coronary artery disease, health related quality of life, sleep quality, sleep-activity rhythm.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-76678OAI: oai:DiVA.org:liu-76678DiVA: diva2:515804
Available from: 2012-04-16 Created: 2012-04-16 Last updated: 2012-04-17Bibliographically approved
In thesis
1. Sleep-Wake-Activity and Health-Related Quality of Life in Patients with Coronary Artery Disease and evaluation of an individualized non-pharmacological programme to promote self-care in sleep
Open this publication in new window or tab >>Sleep-Wake-Activity and Health-Related Quality of Life in Patients with Coronary Artery Disease and evaluation of an individualized non-pharmacological programme to promote self-care in sleep
2012 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Sleep is a basic need, important to physical and psychological recovery. Insomnia implies sleep-related complaints, such as difficulty falling asleep, difficulty staying asleep, early awakening, or non-restorative sleep (NRS) in an individual who has adequate circumstances and opportunity to sleep.  Insomnia is also related to impairment of daytime functions. The prevalence of reported sleep disturbances varies between 15% and 60% in patients with coronary artery disease (CAD) up to five years after intervention. Disturbed sleep may have a negative impact on self-care capacity and behaviours. Little attention has been given to evaluation of sleep promotion through individualized non-pharmacological interventions among CAD patients.

The overall aim of this thesis was to describe the impact of sleep quality and disrupted sleep on health-related quality of life (HRQoL) in patients with stable CAD, in comparison to a population-based group. The objective was also to evaluate an individualized non-pharmacological programme to promote self-care in sleep.

Four studies were conducted during seven years, starting in 2001. Patients from six hospitals in the south of Sweden were invited to participate. In addition, an age and gender matched population-based group was randomly selected during the same period as the patients and was used for comparison with the CAD patients in two of the studies. Data was collected through interviews, self-reported questionnaires, a study specific sleep diary and actigraphy registrations. A pretest-posttest control design was used to evaluate whether an individualized non-pharmacological intervention programme could promote self-care in sleep-activity in CAD patients.

The results showed a high prevalence of insomniac CAD patients out of whom a large proportion were non-rested insomniacs. This showed that NRS is one of the core symptoms of insomnia. On the other hand there were weak or non-significant gender differences with increasing insomnia severity. Severe insomniac CAD patients displayed a two or threefold higher presleep arousal or anxiety score and were more limited in taking physical exercise than the general population. Generally low sleep efficiency (SE%) was revealed in the studies, particularly among severe non-rested insomniac CAD patients.

Among CAD patients, the individualized non-pharmacological programme to promote self-care in sleep-activity indicated improvements in sleep and HRQoL.

This thesis elucidates the importance of focusing on the individual’s perception of their sleep-activity and health in their local context and supporting self-care management. Furthermore, it is of importance that nurses set individual goals together with the patient in order to increase self-efficacy to promote HRQoL.

Place, publisher, year, edition, pages
Linköping: Linköping University Electronic Press, 2012. 107 p.
Series
Linköping University Medical Dissertations, ISSN 0345-0082 ; 1272
Keyword
Actigraphy, coronary artery disease, health-related quality of life, insomnia, non-pharmacological programme, nursing, self-care management, sleep-activity, sleep quality
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-76681 (URN)978-91-7393-029-1 (ISBN)
Public defence
2012-04-03, Berzeliussalen, Campus US, Linköpings universitet, Linköping, 13:00 (Swedish)
Opponent
Supervisors
Available from: 2012-04-17 Created: 2012-04-16 Last updated: 2012-07-09Bibliographically approved

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Johansson, AnnaSvanborg, EvaEdéll-Gustafsson, Ulla

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Department of Medical and Health SciencesFaculty of Health SciencesDepartment of Clinical and Experimental MedicineDepartment of Neurophysiology UHLNursing Science
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