liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Bone mass development in patients with Duchenne and Becker muscular dystrophies: a 4-year clinical follow-up
University of Gothenburg.
Linköping University, Department of Clinical and Experimental Medicine, Clinical Chemistry. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Centre for Diagnostics, Department of Clinical Chemistry.
University of Gothenburg.
University of Gothenburg.
Show others and affiliations
2012 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 101, no 4, 424-432 p.Article in journal (Refereed) Published
Abstract [en]

Aim: To investigate the longitudinal development of bone mass in patients with Duchenne and Becker muscular dystrophies and to study the impact of muscle strength and motor function on bone mass in these patients. less thanbrgreater than less thanbrgreater thanMethods: Eighteen patients with Duchenne muscular dystrophy (2.3-19.7 years at baseline) and six patients with the milder Becker muscular dystrophy (10.8-18.9 years at baseline) were followed during a 4-year period with respect to areal bone mineral density (BMD), motor function and muscle strength. less thanbrgreater than less thanbrgreater thanResults: Greater bone mineral accretion was observed in the Becker patient group compared with the age-related Duchenne group above 10 years of age, and the older patients with Duchenne experienced decreased femoral neck BMD during the study period. In the study group, significant correlations were found between BMD in the lower extremities and muscle function parameters. less thanbrgreater than less thanbrgreater thanConclusions: The differences in BMD between patients with Duchenne and Becker as well as between different bone measurement sites demonstrated in the present study point out the importance of preserving muscle strength and motor function in patients with muscular dystrophy. Moreover; it highlights the value of performing region-specific analysis of the bone quality in these patients.

Place, publisher, year, edition, pages
Wiley-Blackwell , 2012. Vol. 101, no 4, 424-432 p.
Keyword [en]
Bone densitometry, Bone metabolism markers, Children and adolescents, Disability, Dual-energy X-ray absorptiometry
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-76808DOI: 10.1111/j.1651-2227.2011.02532.xISI: 000300973200031OAI: oai:DiVA.org:liu-76808DiVA: diva2:516843
Note
Funding Agencies|Swedish Society of Medicine||Goteborg Medical Society||Majblomman Foundation||Folke Bernadotte Foundation||County Council of Ostergotland||Swedish Association of Persons with Neurological Disabilities||Available from: 2012-04-20 Created: 2012-04-20 Last updated: 2017-12-07

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Magnusson, Per

Search in DiVA

By author/editor
Magnusson, Per
By organisation
Clinical ChemistryFaculty of Health SciencesDepartment of Clinical Chemistry
In the same journal
Acta Paediatrica
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 81 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf