liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Insulin signaling - mathematical modeling comes of age
Linköping University, Department of Clinical and Experimental Medicine. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Cell Biology. Linköping University, Faculty of Health Sciences.
Linköping University, Department of Clinical and Experimental Medicine, Cell Biology. Linköping University, Faculty of Health Sciences.
2012 (English)In: Trends in endocrinology and metabolism, ISSN 1043-2760, E-ISSN 1879-3061, Vol. 23, no 3, 107-115 p.Article, review/survey (Refereed) Published
Abstract [en]

Signaling pathways that only a few years ago appeared simple and understandable, albeit far from complete, have evolved into very complex multi-layered networks of cellular control mechanisms, which in turn are integrated in a similarly complex whole-body level of control mechanisms. This complexity sets limits for classical biochemical reasoning, such that a correct and complete analysis of experimental data while taking the full complexity into account is not possible. In this Opinion we propose that mathematical modeling can be used as a tool in insulin signaling research, and we demonstrate how recent developments in modeling - and the integration of modeling in the experimental process - provide new possibilities to approach and decipher complex biological systems more efficiently.

Place, publisher, year, edition, pages
Elsevier , 2012. Vol. 23, no 3, 107-115 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-76962DOI: 10.1016/j.tem.2011.12.007ISI: 000302444900002OAI: oai:DiVA.org:liu-76962DiVA: diva2:523992
Note
Funding Agencies|European Commission Network of Excellence Biosim||Novo Nordisk Foundation||Swedish Diabetes Association||Swedish Research Council||Lions||Available from: 2012-04-27 Created: 2012-04-27 Last updated: 2017-12-07

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Nyman, ElinCedersund, GunnarStrålfors, Peter

Search in DiVA

By author/editor
Nyman, ElinCedersund, GunnarStrålfors, Peter
By organisation
Department of Clinical and Experimental MedicineFaculty of Health SciencesCell Biology
In the same journal
Trends in endocrinology and metabolism
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 248 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf