Spectral and in vitro antimicrobial properties of 2-oxo-4-phenyl-6-styryl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid transition metal complexes
2012 (English)In: Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, ISSN 1386-1425, Vol. 93, 348-353 p.Article in journal (Refereed) Published
2-oxo-4-phenyl-6-styryl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid (ADP) was complexed with acetates of Mn(II), Ni(II), Cu(II) and Zn(II). The structures of the ligand and its metal complexes were characterized by microanalysis, IR. NMR, UV-vis spectroscopy, magnetic susceptibility and TGA-DTA analyses. Octahedral and square planar geometries were suggested for the complexes in which the central metal ion coordinated with -O donors of ligand and acetate ions. Each ligand binds the metal using carboxylate oxygens. The ligand and complexes were evaluated for their antimicrobial activities against different species of pathogenic bacteria and fungi. The present novel pyrimidine containing complexes could constitute a new group of antibacterial and antifungal agents.
Place, publisher, year, edition, pages
Elsevier , 2012. Vol. 93, 348-353 p.
Pyrimidine transition metal complexes, Spectral, Octahedral, Square planar geometry, Anti-microbial activity
National CategoryEngineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-77852DOI: 10.1016/j.saa.2012.02.096ISI: 000303956500052OAI: oai:DiVA.org:liu-77852DiVA: diva2:529736
Funding Agencies|UGC, New Delhi||2012-05-312012-05-312012-05-31