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Needle-Type Glucose Sensor Based on Functionalized Graphene
Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
Linköping University, Department of Science and Technology, Physics and Electronics. Linköping University, The Institute of Technology.ORCID iD: 0000-0001-6235-7038
2012 (English)In: Journal of Biosensors and Bioelectronics, ISSN 2155-6210, Vol. 3, no 1Article in journal (Refereed) Published
Abstract [en]

We demonstrate a novel, highly efficient glucose sensor based on functionalized graphene. Glucose oxidase (GOD) immobilization has been apprehendedbythe direct interaction between carboxyl acid groups of the reduced graphene oxide (RGO) and amines of GOD together with the electrostatic interactions existing between the positively charged polymeric ionic liquid (PIL) and GOD. This combined system can provide a favorable microenvironment for the GOD to retain its good bioactivity. The enzyme-coated graphene biosensor exhibited glucose-dependent electrochemical measurements against an Ag/AgCl reference electrode. The resulting sensor show broad range detection, up to 100 mM glucose concentration, with a sensitivity of 5.59 μA/ decade. It was found that glucose biosensor based on functionalized graphene can be seen as an effective candidate for the detection of sugar concentration in clinical diagnoses.

Place, publisher, year, edition, pages
2012. Vol. 3, no 1
National Category
Natural Sciences
Identifiers
URN: urn:nbn:se:liu:diva-78677DOI: 10.4172/2155-6210.1000114OAI: oai:DiVA.org:liu-78677DiVA: diva2:534718
Available from: 2012-06-18 Created: 2012-06-18 Last updated: 2014-01-15Bibliographically approved
In thesis
1. Graphene and ZnO Nanostructures for Nano- Optoelectronic & Biosensing Applications
Open this publication in new window or tab >>Graphene and ZnO Nanostructures for Nano- Optoelectronic & Biosensing Applications
2012 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

There has been a remarkable excitement in graphene research since the famous discovery in 2004 by isolating a monolayer with the help of scotch tape. Graphene, merely a single layer of carbon atoms, is progressively making inroads into a wide range of applications, from ballistic electronics to biosensors to flexible/transparent displays. Graphene is a matchless material that is strong, light, transparent, and an excellent conductor of heat and electricity. On the other hand, zinc oxide (ZnO) is a wide band semiconductor that demonstrates excellent electrical, optical, catalytic and sensing properties and has numerous applications in various fields. ZnO is a natural n-type semiconductor due to the presence of intrinsic defects such as Zn interstitials and O vacancies that also contribute strongly to optical emissions in the visible region.

The amalgamation of the exceptional properties of graphene with good semiconducting properties of ZnO can pave the way towards the realization of future devices (LED, biosensors, photovoltaics etc.).

In this thesis, graphene nanosheets and zinc oxide (ZnO) nanostructures have beensuccessfully synthesized by using chemical vapor deposition (CVD), vapor liquidsolid (VLS) or wet chemistry routines. These nanostructures were used to fabricatenano and optoelectronic devices, including field effect transistors (FETs), lightemitting diodes (LEDs), UV detectors and biosensors. Both nanomaterial’s propertiesand performances of the devices have been characterized and reported.

Place, publisher, year, edition, pages
Linköping: Linköping University Electronic Press, 2012. 80 p.
Series
Linköping Studies in Science and Technology. Dissertations, ISSN 0345-7524 ; 1458
National Category
Natural Sciences
Identifiers
urn:nbn:se:liu:diva-78697 (URN)978-91-7519-869-9 (ISBN)
Public defence
2012-05-29, K3, Kåkenhus, Campus Norrköping, Linköpings universitet, Norrköping, 10:15 (English)
Opponent
Supervisors
Available from: 2012-06-18 Created: 2012-06-18 Last updated: 2014-01-15Bibliographically approved

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ul Hasan, KamranAsif, Muhammad H.Willander, Magnus

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