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Super-selective venous sampling in conjunction with quickPTH for patients with persistent primary hyperparathyroidism: report of five cases
Linköping University, Department of Clinical and Experimental Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Centre for Surgery, Orthopaedics and Cancer Treatment, Department of Surgery in Östergötland.
Linköping University, Department of Clinical and Experimental Medicine, Surgery. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Centre for Surgery, Orthopaedics and Cancer Treatment, Department of Surgery UHL.
Östergötlands Läns Landsting, Centre for Surgery, Orthopaedics and Cancer Treatment, Department of Surgery UHL. Linköping University, Department of Clinical and Experimental Medicine, Surgery. Linköping University, Faculty of Health Sciences.
Östergötlands Läns Landsting, Centre for Surgery, Orthopaedics and Cancer Treatment, Department of Surgery UHL.
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2012 (English)In: Surgery today (Print), ISSN 0941-1291, E-ISSN 1436-2813, Vol. 42, no 6, 570-576 p.Article in journal (Refereed) Published
Abstract [en]

Selective venous sampling (SVS) helps to interpret imaging results in patients with persistent primary hyperparathyroidism (pHPT). However, one of the drawbacks of conventional SVS may be low "spatial resolution", depending on the sample size. We modified SVS in the following way: first, patients underwent conventional SVS with up to 11 parathyroid hormone (PTH) samples taken. The quickPTH assay was used to measure PTH levels. The patients subsequently underwent super-selective venous sampling (super-SVS) in the region with the highest quickPTH level in the same session. The subjects were five consecutive patients with persistent pHPT investigated by various imaging techniques, none of which was considered conclusive. Therefore, all five patients underwent super-SVS, which was done successfully in four. Re-evaluation of the imaging results of these four patients resulted in localization of the parathyroid adenoma. Curative surgery was performed successfully in all four patients during the study period. Super-SVS increases the "spatial resolution" of conventional SVS and may have advantages when imaging results of patients with persistent pHPT are interpreted. Its true value must be analyzed in larger studies.

Place, publisher, year, edition, pages
Springer Verlag (Germany) , 2012. Vol. 42, no 6, 570-576 p.
Keyword [en]
Primary hyperparathyroidism, Selective venous sampling, QuickPTH
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-78807DOI: 10.1007/s00595-012-0119-7ISI: 000304509100010OAI: oai:DiVA.org:liu-78807DiVA: diva2:536053
Available from: 2012-06-21 Created: 2012-06-21 Last updated: 2017-12-07

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Gimm, OliverArnesson, Lars-GunnarOlofsson, PiaJuhlin, Claes

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Gimm, OliverArnesson, Lars-GunnarOlofsson, PiaJuhlin, Claes
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Department of Clinical and Experimental MedicineFaculty of Health SciencesDepartment of Surgery in ÖstergötlandSurgeryDepartment of Surgery UHL
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