Human postburn oedema measured with the impression method
1993 (English)In: Burns, ISSN 0305-4179, E-ISSN 1879-1409, Vol. 19, no 6, 479-489 p.Article in journal (Refereed) Published
The course of tissue swelling in human non-injured skin after burn injury was investigated with a non-invasive impression method that measures force and tissue fluid translocation during mechanical compression of the skin. Time-dependent changes in the fluid translocation and the interstitial-pressure related to impression force were measured on 11 occasions, during 3 weeks, in seven patients postburn. A mathematical model was fitted to the impression force curves and the parameters of the model depicted the time-dependent compartmental fluid shift in the postburn generalized oedema. Tissue fluid translocation increased significantly (P < 0.05) up to a maximum value after 6 days postburn and declined thereafter. This indicated a continuous increase in the generalized postburn oedema for the first 6 days postburn. Impression force at 3 weeks postburn was significantly lower (P < 0.001) as compared with the half-day postburn value, indicating an increased tissue pressure during the first days postburn. Parameter analysis indicated a flux of water-like fluid from the vasculature to the interstitial space during the first 6 days postburn. The spread of the values registered between different measurement sites was, however, large.
Place, publisher, year, edition, pages
1993. Vol. 19, no 6, 479-489 p.
National CategoryMedical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-79563DOI: 10.1016/0305-4179(93)90003-QOAI: oai:DiVA.org:liu-79563DiVA: diva2:543581