Assembly of Polypeptide-Functionalized Gold Nanoparticles through a Heteroassociation- and Folding-Dependent Bridging
2008 (English)In: Nano letters (Print), ISSN 1530-6984, Vol. 8, no 8, 2473-2478 p.Article in journal (Refereed) Published
Gold nanoparticles were functionalized with a synthetic polypeptide, de novo-designed to associate with a charge complementary linker polypeptide in a folding-dependent manner. A heterotrimeric complex that folds into two disulphide-linked four-helix bundles is formed when the linker polypeptide associates with two of the immobilized peptides. The heterotrimer forms in between separate particles and induces a rapid and extensive aggregation with a well-defined interparticle spacing. The aggregated particles are redispersed when the disulphide bridge in the linker polypeptide is reduced.
Place, publisher, year, edition, pages
ACS Publications , 2008. Vol. 8, no 8, 2473-2478 p.
National CategoryChemical Sciences
IdentifiersURN: urn:nbn:se:liu:diva-15121DOI: 10.1021/nl8014796OAI: oai:DiVA.org:liu-15121DiVA: diva2:54446
The original title of this article was "Assembly of Decorated Gold Nanoparticles through a Hetero-Association and Folding-Dependent Bridging".2008-10-162008-10-162014-10-08