Perioperative autotransfusion and functional coagulation analysis in total hip replacement
1995 (English)In: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 39, no 3, 390-395 p.Article in journal (Refereed) Published
Functional coagulation analyses like Sonoclot and thromboelastography have not been evaluated during perioperative autotransfusion. We have prospectively studied three different transfusion regimes in 45 patients undergoing total hip arthroplasty. Blood losses were replaced either with heterologous erythrocyte concentrate (group I), intra- and postoperative autotransfusion of blood salvaged with cellsaver technique (group II) or predonated autologous erythrocyte concentrates together with salvaged blood (group III). Routine and functional coagulation analyses with a Sonoclot were performed preoperatively, 6 hours postoperatively (6 h), day 1–5 and 10. An early postoperative hypo- and late postoperadve hypercoagulative phase could be detected with Sonoclot signs of platelet function and fibrin deposition in all groups. Sonoclot coagulation analyses better correlated to both blood loss and dextran dosage than APTT and platelet count in the routine coagulation analyses. Functional coagulation analysis has a potential use in individualizing plasmasubstitution and thromboprophylaxis regimes during autotransfusion in THR.
Place, publisher, year, edition, pages
1995. Vol. 39, no 3, 390-395 p.
Anesthetics, local-bupivacaine, anesthetic techniques, spinal anesthesia, autotransfusion, coagulation analysis: low molecular weight heparin, dextran
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-79954DOI: 10.1111/j.1399-6576.1995.tb04083.xOAI: oai:DiVA.org:liu-79954DiVA: diva2:544820