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The scale and nature of adverse events in hospital – Is an event drug-related?
Nordic School of Public Health NHV, Sweden .
Uppsala Monitoring Centre, WHO Collaborating Centre for International Drug Monitoring Sweden.
Linköping University, Department of Medical and Health Sciences, Clinical Pharmacology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Center for Diagnostics, Department of Clinical Pharmacology.
2012 (English)In: BMJ. British Medical Journal, ISSN 0959-8146, E-ISSN 0959-535X, Vol. 344, 10.1136/bmj.e832Article in journal, Letter (Other academic) Published
Abstract [en]

We commend Wilson and colleagues1 for their excellent study providing valuable evidence on the frequency and nature of adverse events in hospitals in transitional economies. Wilson and colleagues defined an adverse event as “an unintended injury that resulted in temporary or permanent disability or death (including increased length of stay or readmission) and that was associated with healthcare management rather than the underlying disease”, and found that 8.2% of the 15 548 reviewed records included at least one adverse event. The most common adverse events were therapeutic errors (34% of all adverse events), diagnostic events (19%), and operation-related events (18%). Drug-related adverse events represented only 4% of all adverse events, and were present in 0.3% of all records. Thus, drug-related events were markedly less frequent than in western studies,2 as the authors acknowledge. Wilson and colleagues imply that less frequent use of medicines in transitional economies may contribute to fewer drug-related events, and argue that improvements are needed in the diagnostic and therapeutic steps in the care of patients.

Place, publisher, year, edition, pages
2012. Vol. 344, 10.1136/bmj.e832
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-80997DOI: 10.1136/bmj.e832OAI: diva2:549743
Available from: 2012-09-05 Created: 2012-09-05 Last updated: 2015-10-28Bibliographically approved

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Hägg, Staffan
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Clinical PharmacologyFaculty of Health SciencesDepartment of Clinical Pharmacology
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