Embedded Adaptive Optics for Ubiquitous Lab-on-a-Chip Readout on Intact Cell Phones
2012 (English)In: Sensors, ISSN 1424-8220, Vol. 12, no 7, 8586-8600 p.Article in journal (Refereed) Published
The evaluation of disposable lab-on-a-chip (LOC) devices on cell phones is an attractive alternative to migrate the analytical strength of LOC solutions to decentralized sensing applications. Imaging the micrometric detection areas of LOCs in contact with intact phone cameras is central to provide such capability. This work demonstrates a disposable and morphing liquid lens concept that can be integrated in LOC devices and refocuses micrometric features in the range necessary for LOC evaluation using diverse cell phone cameras. During natural evaporation, the lens focus varies adapting to different type of cameras. Standard software in the phone commands a time-lapse acquisition for best focal selection that is sufficient to capture and resolve, under ambient illumination, 50 mu m features in regions larger than 500 x 500 mu m(2). In this way, the present concept introduces a generic solution compatible with the use of diverse and unmodified cell phone cameras to evaluate disposable LOC devices.
Place, publisher, year, edition, pages
MDPI , 2012. Vol. 12, no 7, 8586-8600 p.
adaptive optics, lab-on-a-chip readout, optical chemical sensing, ubiquitous sensing, cell phones
National CategoryEngineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-81222DOI: 10.3390/s120708586ISI: 000306796500010OAI: oai:DiVA.org:liu-81222DiVA: diva2:551054
Funding Agencies|Linkoping Centre for Life Science Technologies (LIST), Sweden||Thammasat University of Thailand for Pakorn Preechaburana||2012-09-102012-09-102015-06-01