Optical Measurements for Guidance during Deep Brain Stimulation Implantation
2012 (English)Conference paper (Refereed)
Deep brain stimulation (DBS) is an established treatment for Parkinson’s disease and related movement disorders. The success of DBS is highly dependent on electrode location, electrical parameter settings and the surgical procedure. In this paper an overview of the current status of optical measurements for intracerebral guidance performed during DBS implantation is presented. Laser Doppler perfusion monitoring and/or reflection spectroscopy measurements have been done in relation to more than 70 DBS lead implantations to wards targets in the deep brain structures. The techniques have also been compared with impedance monitoring, and simulation of the measurement depth has been done with Monte Carlo technique. These studies show that grey-white matter boundaries can be determined with a resolution higher than for both impedance measurements and magnetic resonance imaging.
Place, publisher, year, edition, pages
National CategoryEngineering and Technology
IdentifiersURN: urn:nbn:se:liu:diva-81326OAI: oai:DiVA.org:liu-81326DiVA: diva2:551649
World Congress on Biomedical Engineering and Physics 2012, May 26-31, Beijing, China