The Cost Effectiveness of Helicobacter pylori Eradication versus Maintenance and Episodic Treatment in Duodenal Ulcer Patients in Sweden
1995 (English)In: PharmacoEconomics (Auckland), ISSN 1170-7690, Vol. 8, no 5, 410-427 p.Article in journal (Refereed) Published
This study compares the cost effectiveness of Helicobacter pylori eradication and conventional treatment in duodenal ulcer patients treated by a general practitioner. Using a Markov chain approach, Swedish cost data and a study period of 5 years, we conclude that H. pylori eradication with omeprazole and appropriate antibiotics is a cost-effective alternative compared with both maintenance and episodic treatment. Of the patients entering the eradication strategy, most are cured and will have no relapse during a 5-year period. H. pylori eradication results in higher initial costs but, because of a very low risk of recurrence after successful eradication, the expected future costs are reduced. The investment pays off within 1 year when compared with maintenance treatment, and within 3 years when compared with episodic treatment.
Place, publisher, year, edition, pages
1995. Vol. 8, no 5, 410-427 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-81388PubMedID: 10160075OAI: oai:DiVA.org:liu-81388DiVA: diva2:552152