A Device for Measurement of Capillary Refilling Time
Independent thesis Advanced level (degree of Master (Two Years)), 80 credits / 120 HE creditsStudent thesis
The main objective of this project is to design, construct and validate a portable prototype of a device that is capable of performing a test to accurately measure Capillary Refilling Time (CRT), and to analyze the results with defined parameters; force, area, pressure (compression) and time. This prototype is dedicated to study and evaluate CRT readouts for different pressure values, collected from healthy subjects.The presented prototype of this study is capable of producing skin compressing and to measure the refilling time of capillaries following this compression. This prototype introduces accuracy, mechanical reproducibility and controlling options for the applied pressure and compression time. The presented prototype is non-invasive, portable and it can be used to conduct more CRT tests and other capillary refilling studies.CRT measurement is done by calculating time interval starting from the first point when the applied pressure is released; ending with the recording point at the time when the concentration of red blood cells has reached the level of its pre-occlusion values.Based on the calculated CRT values and the number of iterations of the test in CRT tables, one can observe that given the same applied pressure value, CRT values do not significantly vary when the test is repetitively conducted on the same subject and on the same site.
Place, publisher, year, edition, pages
2012. , 61 p.
Capillary Refilling Time Measurement Device, Capillary Refilling Response, Capillary Occlusion Time
Medical Engineering Medical Equipment Engineering Medical Laboratory and Measurements Technologies
IdentifiersURN: urn:nbn:se:liu:diva-81496ISRN: LiTH-IMT/MASTER-EX--12/017--SEOAI: oai:DiVA.org:liu-81496DiVA: diva2:553038
Subject / course
Master's Program Biomedical Engineering
2012-09-03, IMT1, Campus US, Linköping, 13:00 (English)
Latorre, Malcolm, Doctoral Student
Nilsson, Gert, Professor