Expression of inducible nitric oxide synthase and nitrotyrosine in granuloma-associated macrophages from patients with tuberculosis
(English)Manuscript (preprint) (Other academic)
NO produced by the inducible nitric oxide synthase (iNOS) is important in host defense against M tuberculosis. We investigated the expression of iNOS and nitrotyrosine (Ntyr) in untreated patients with tuberculosis. Many iNOS/Ntyr reactive macrophages were observed in pleuro-pulmonary granulomas comrrming the presence of high-output NO-production in human tuberculosis.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-81719OAI: oai:DiVA.org:liu-81719DiVA: diva2:555720