Very late mucosal relapse in a girl with coeliac disease
1993 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 82, no 10, 887-889 p.Article in journal (Refereed) Published
Small bowel biopsy in a 4–year-old girl with symptoms suggestive of coeliac disease revealed subtotal villous atrophy. The mucosa healed on a gluten-free diet. From the age of 7 years, the girl was challenged with gluten. Annual biopsies showed normal or nearly normal mucosa specimens. At 21 years of age, after 14 years of gluten challenge, a mucosal relapse was found and a gluten-free diet was reinstituted. A biopsy one year later showed a normal mucosa. From this case report it is apparent that a patient with a past history of subtotal villous atrophy, which after a preceding period of gluten-free diet does not recur within two years of gluten challenge, must be followed carefully, so as not to miss a late relapse.
Place, publisher, year, edition, pages
1993. Vol. 82, no 10, 887-889 p.
National CategoryMedical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-84482DOI: 10.1111/j.1651-2227.1993.tb17636.xOAI: oai:DiVA.org:liu-84482DiVA: diva2:559506