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Flow Potentiometric Injection Analysis of Uric Acid Using Lipid Stabilized Films with Incorporated Uricase on ZnO Nanowires
National Technical University of Athens, Greece .
National Technical University of Athens, Greece .
National Technical University of Athens, Greece .
University of Athens, Greece .
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2012 (English)In: Electroanalysis, ISSN 1040-0397, E-ISSN 1521-4109, Vol. 24, no 8, 1719-1725 p.Article in journal (Refereed) Published
Abstract [en]

A novel potentiometric uric acid biosensor was fabricated by immobilization of uricase into stabilized lipid films using zinc oxide (ZnO) nanowires as measuring electrode. Uricase was incorporated into the lipid film prior polymerization on the surface of well aligned ZnO nanowires resulting in a sensitive, selective, stable and reproducible uric acid biosensor. The potentiometric response was twice as large from previously reported values due to the presence of a cationic lipid in the lipid film. The sensor response had no interferences by normal concentrations of ascorbic acid, glucose, urea, proteins and lipids.

Place, publisher, year, edition, pages
Wiley-VCH Verlag Berlin , 2012. Vol. 24, no 8, 1719-1725 p.
Keyword [en]
ZnO Nanowires, Potentiometric nanosensors, Uricase, Uric acid, Stabilized lipid films, Implanted electrochemical nanodevices
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-84747DOI: 10.1002/elan.201200220ISI: 000308398100005OAI: diva2:561488
Available from: 2012-10-19 Created: 2012-10-19 Last updated: 2014-01-15

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Willander, MagnusIsrar Qadir, Muhammad
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Physics and ElectronicsThe Institute of TechnologyDepartment of Science and Technology
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ReferencesLink to record
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