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Medline search validity for randomised controlled trials in different areas of dental research
Department of Health Sciences, Knstianstad University, Kristiadstad, Sweden.
Department of Health Sciences, Knstianstad University, Kristiadstad, Sweden.
2002 (English)In: British Dental Journal, ISSN 0007-0610, E-ISSN 1476-5373, Vol. 192, no 2, 97-99 p.Article in journal (Refereed) Published
Abstract [en]

Objective To determine the validity of Medline searches for randomised controlled trials in dental research (RCT-Ds), using the medical subject headings (MeSH-terms).

Design The Medline database was searched for randomised controlled trials in dental research (RCT-Ds) published in 1999 and with MeSH-terms corresponding to different areas of dental research. All RCT-Ds were manually examined for relevance to the different areas of dental research and cross-tabulated against the Medline search results. The sensitivity, specificity, positive (precision) and negative predictive values, as well as the accuracy of the search results were calculated.

Results The highest validity in the Medline searches for RCT-Ds was seen for endodontics, followed by orthodontics, whereas the lowest validity was seen for pediatric dentistry and public health dentistry. For pediatric dentistry the MeSH-term searches had too low a sensitivity for adequate location of RCT-Ds.

Conclusions MeSH-term searches on Medline are a useful tool for rapid location of RCT-Ds in most areas of dental research. However, there is a vast variation in the search validity. More refined search strategies are required to locate RCT-Ds in areas of dental research with low search validity.

Place, publisher, year, edition, pages
2002. Vol. 192, no 2, 97-99 p.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-84948DOI: 10.1038/sj.bdj.4801303OAI: oai:DiVA.org:liu-84948DiVA: diva2:563123
Available from: 2012-10-29 Created: 2012-10-29 Last updated: 2017-12-07
In thesis
1. Randomised clinical trials and evidence-based general dentistry
Open this publication in new window or tab >>Randomised clinical trials and evidence-based general dentistry
2004 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

A growing number of scientific publications and new treatment modalities have increased the difficulties of keeping up to date with the latest research evidence in clinical practice. Therefore, evidence-based dentistry and medicine (EBDM) has evolved as an attempt to summarise current best evidence.

The overall aim of this thesis was to study the availability and the methodological quality of randomised controlled trials (RCTs) in dental (RCT-Ds) and medical (RCT-Ms) research, and publications describing epidemiological registration methods of dental caries. It also examines the applicability of evidence-based methods to general dental practice.

The most important findings were that the armual number of publications in dental research showed a decreasing trend from 1969 to 1999, whereas medical research increased. The armual number of clinical trials (CTs), meta-analyses and RCTs increased, but represented just a fraction of all publications in both dental and medical research. Medical subject heading (MeSH) searches provided an overall adequate method for rapid location of RCT-Ds on Medline for most areas of dental research. The quality of RCT-Ds and RCT-Ms were generally inadequate. There was no correlation between the quality of RCTs and Journal Impact Factor. The armual number of publications, CTs and RCTs in periodontal research (RCT-Ps) increased during 1980-2000. A few clinical research areas dominated the RCT-Ps. Most of the RCT-Ps were published in just two different dental journals. Validation methodology in publications describing epidemiological methods for registering dental caries was inadequate according to EBDM recommendations and needs to be improved.

Place, publisher, year, edition, pages
Linköping: Linköpings universitet, 2004. 57 p.
Series
Linköping University Medical Dissertations, ISSN 0345-0082 ; 865
Keyword
Dental care, dental research, epidemiological methods, evidence-based medicine, Medline, randomized controlled trials, validity
National Category
Social Sciences
Identifiers
urn:nbn:se:liu:diva-22686 (URN)1978 (Local ID)91-7373-839-5 (ISBN)1978 (Archive number)1978 (OAI)
Public defence
2004-11-12, Aulan, Hälsans Hus, Hälsouniversitetet, Linköping, 13:00 (Swedish)
Opponent
Available from: 2009-10-07 Created: 2009-10-07 Last updated: 2012-10-29Bibliographically approved

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Sjögren, Petteri

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