Low level of antimicrobial resistance in Escherichia coli among Swedish nursing home residents
2013 (English)In: Scandinavian journal of infectious diseases, ISSN 1651-1980, Vol. 45, no 2, 117-123 p.Article in journal (Refereed) Published
Background: Screening for bacterial colonization and antimicrobial resistance (AMR) among a defined population could aid in the identification of at-risk populations and provide targets for antibiotic stewardship and infection control programmes. Methods: Two hundred and sixty-eight participants at 11 Swedish nursing homes underwent serial screening for colonization with Escherichia coli between March 2008 and September 2010. Seventy-two of the 268 participants (27%) were male. The median age was 85 y. Samples were collected from urine, the rectal mucosa, the groin, and active skin lesions. Results: Two hundred and nine of 268 participants (78%) were colonized with E. coli at any body site/fluid. The specific colonization rates were 81% (rectum), 48% (urine), 30% (groin), 59% (unknown), and 13% (skin lesion). An antibiotic-resistant E. coli isolate was identified in 18% of all participants regardless of colonization status; all together, 87 resistant isolates were detected. Only 1 participant carried isolates with resistance to third-generation cephalosporins (cefotaxime and ceftazidime). Conclusions: The presence of resistance was generally low, and the greater part of the resistant cases was connected with 3 common antibiotics: ampicillin, trimethoprim/sulfamethoxazole, and ciprofloxacin. In spite of generally increasing resistance against third-generation cephalosporins in E. coli in Sweden, this study does not implicate residence at a Swedish nursing home as a risk factor for the acquisition of expressed cephalosporin resistance.
Place, publisher, year, edition, pages
Informa Healthcare, 2013. Vol. 45, no 2, 117-123 p.
Mass screening, colonization, nursing homes, drug resistance, bacterial, Escherichia coli
National CategoryMedical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-85105DOI: 10.3109/00365548.2012.717232ISI: 000313677200006PubMedID: 22992114OAI: oai:DiVA.org:liu-85105DiVA: diva2:564710