Microscopic colitis: Current status, present and future challenges Statements of the European Microscopic Colitis Group
2012 (English)In: Journal of Crohn's and Colitis, ISSN 1873-9946, EISSN 1876-4479, Vol. 6, no 9, 932-945 p.Article in journal (Refereed) Published
Microscopic colitis (MC) is an inflammatory bowel disease presenting with chronic, non-bloody watery diarrhoea and few or no endoscopic abnormalities. The histological examination reveals mainly two subtypes of MC, lymphocytic or collagenous colitis. Despite the fact that the incidence in MC has been rising over the last decades, research has been sparse and our knowledge about MC remains limited. Specialists in the field have initiated the European Microscopic Colitis Group (EMCG) with the primary goal to create awareness on MC. The EMCG is furthermore a forum with the intention to promote clinical and basic research. In this article statements and comments are given that all members of the EMCG have considered being of importance for a better understanding of MC. The paper focuses on the newest updates in epidemiology, symptoms and diagnostic criteria, pathophysiology and highlights some unsolved problems. Moreover, a new treatment algorithm is proposed on the basis of new evidence from well-designed, randomized control trials.
Place, publisher, year, edition, pages
Elsevier , 2012. Vol. 6, no 9, 932-945 p.
Microscopic colitis, Collagenous colitis, Lymphocytic colitis, Budesonide
National CategoryMedical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-85622DOI: 10.1016/j.crohns.2012.05.014ISI: 000309990400009OAI: oai:DiVA.org:liu-85622DiVA: diva2:572067
Funding Agencies|Tillots Pharma||Falk Pharma||Tillotts Pharma||Ferring||MSD||Astra-Zeneca||Falk Foundation, Germany||MEDA, Sweden||2012-11-262012-11-262015-03-25