A laser Doppler system for monitoring of intracerebral microcirculation
2012 (English)In: Conf Proc IEEE Eng Med Biol Soc., ISSN 1557-170X, 1988-1991 p.Article in journal (Refereed) Published
A two-channel standard laser Doppler perfusion monitor has been adapted for intracerebral measurements. Software developed in Labview makes it possible to present the microvascular perfusion, total light intensity (TLI), heart rate and trend curves in real-time during surgery. A custom-made optical probe was designed in order to enable easy fixation during brain surgery. The constructed brain probe was evaluated and compared to a standard probe. Both probes presented similar feasibility when used for the skin recordings. In addition, evaluation was done in one patient in relation to tumor resection. Stable perfusion and TLI signals were immediately recorded when the probe was positioned in cerebral tissue. Movement artifacts were clearly seen when the probe was moved to a new site. Recordings in cortex and tumor border showed higher perfusion and lower TLI compared to measurements in subcortical white matter. The calculated heart rate estimate agreed well with the noted value from the electrocardiographic patient monitoring system.
Place, publisher, year, edition, pages
IEEE , 2012. 1988-1991 p.
IdentifiersURN: urn:nbn:se:liu:diva-86150DOI: 10.1109/EMBC.2012.6346346ISI: 000313296502058PubMedID: 23366307ISBN: 978-1-4244-4119-8ISBN: e-978-1-4244-4120-4ISBN: 978-1-4577-1787-1OAI: oai:DiVA.org:liu-86150DiVA: diva2:575176
FunderSwedish Research Council