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A laser Doppler system for monitoring of intracerebral microcirculation
Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation.
Östergötlands Läns Landsting, Reconstruction Centre, Department of Neurosurgery UHL.
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuroscience. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Anaesthetics, Operations and Specialty Surgery Center, Department of Neurosurgery.
Linköping University, The Institute of Technology. Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation.ORCID iD: 0000-0002-0012-7867
2012 (English)In: Conf Proc IEEE Eng Med Biol Soc., ISSN 1557-170X, 1988-1991 p.Article in journal (Refereed) Published
Abstract [en]

A two-channel standard laser Doppler perfusion monitor has been adapted for intracerebral measurements. Software developed in Labview makes it possible to present the microvascular perfusion, total light intensity (TLI), heart rate and trend curves in real-time during surgery. A custom-made optical probe was designed in order to enable easy fixation during brain surgery. The constructed brain probe was evaluated and compared to a standard probe. Both probes presented similar feasibility when used for the skin recordings. In addition, evaluation was done in one patient in relation to tumor resection. Stable perfusion and TLI signals were immediately recorded when the probe was positioned in cerebral tissue. Movement artifacts were clearly seen when the probe was moved to a new site. Recordings in cortex and tumor border showed higher perfusion and lower TLI compared to measurements in subcortical white matter. The calculated heart rate estimate agreed well with the noted value from the electrocardiographic patient monitoring system.                                                                                                                                                      

Place, publisher, year, edition, pages
IEEE , 2012. 1988-1991 p.
National Category
Medical Engineering
URN: urn:nbn:se:liu:diva-86150DOI: 10.1109/EMBC.2012.6346346ISI: 000313296502058PubMedID: 23366307ISBN: 978-1-4244-4119-8ISBN: e-978-1-4244-4120-4ISBN: 978-1-4577-1787-1OAI: diva2:575176
Swedish Research Council
Available from: 2012-12-07 Created: 2012-12-07 Last updated: 2016-05-04Bibliographically approved

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Rejmstad, PeterHillman, JanWårdell, Karin
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The Institute of TechnologyBiomedical InstrumentationDepartment of Neurosurgery UHLDivision of NeuroscienceFaculty of Health SciencesDepartment of Neurosurgery
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