Health-related quality of life and anemia in hospitalized patients with heart failure
2012 (English)In: International Journal of Cardiology, ISSN 0167-5273, E-ISSN 1874-1754, Vol. 161, no 3, 151-155 p.Article in journal (Refereed) Published
Background: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients. less thanbrgreater than less thanbrgreater thanMethods: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class. less thanbrgreater than less thanbrgreater thanResults: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003). less thanbrgreater than less thanbrgreater thanConclusion: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.
Place, publisher, year, edition, pages
Elsevier , 2012. Vol. 161, no 3, 151-155 p.
Hemoglobin, Patient-related outcomes, Health-status measurements, Relationship
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-86647DOI: 10.1016/j.ijcard.2012.05.036ISI: 000311221300016OAI: oai:DiVA.org:liu-86647DiVA: diva2:580097
Funding Agencies|Netherlands Heart Foundation|2000Z003|Ministry of Health, Welfare, and Sport||2012-12-202012-12-202013-09-18