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Health-related quality of life and anemia in hospitalized patients with heart failure
University of Groningen, Netherlands .
University of Groningen, Netherlands .
Linköping University, Department of Medical and Health Sciences, Cardiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Centre, Department of Cardiology UHL. Linköping University, Department of Social and Welfare Studies, Health, Activity, Care.ORCID iD: 0000-0001-7431-2873
University of Groningen, Netherlands .
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2012 (English)In: International Journal of Cardiology, ISSN 0167-5273, E-ISSN 1874-1754, Vol. 161, no 3, 151-155 p.Article in journal (Refereed) Published
Abstract [en]

Background: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients. less thanbrgreater than less thanbrgreater thanMethods: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class. less thanbrgreater than less thanbrgreater thanResults: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003). less thanbrgreater than less thanbrgreater thanConclusion: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.

Place, publisher, year, edition, pages
Elsevier , 2012. Vol. 161, no 3, 151-155 p.
Keyword [en]
Hemoglobin, Patient-related outcomes, Health-status measurements, Relationship
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-86647DOI: 10.1016/j.ijcard.2012.05.036ISI: 000311221300016OAI: diva2:580097

Funding Agencies|Netherlands Heart Foundation|2000Z003|Ministry of Health, Welfare, and Sport||

Available from: 2012-12-20 Created: 2012-12-20 Last updated: 2013-09-18

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