Cancer stem cell markers in common cancers - therapeutic implications
2008 (English)In: Trends in Molecular Medicine, ISSN 1471-4914, E-ISSN 1471-499X, Vol. 14, no 10, 450-460 p.Article, review/survey (Refereed) Published
Rapid advances in the cancer stem cell (CSC) field have provided cause for optimism for the development of more reliable cancer therapies in the future. Strategies aimed at efficient targeting of CSCs are becoming important for monitoring the progress of cancer therapy and for evaluating new therapeutic approaches. Here, we characterize and compare the specific markers that have been found to be present on stem cells, cancer cells and CSCs in selected tissues (colon, breast, liver, pancreas and prostate). We then discuss future directions of this intriguing new research field in the context of new diagnostic and therapeutic opportunities.
Place, publisher, year, edition, pages
Elsevier, 2008. Vol. 14, no 10, 450-460 p.
Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) Biochemistry and Molecular Biology Cell Biology
IdentifiersURN: urn:nbn:se:liu:diva-86923DOI: 10.1016/j.molmed.2008.08.003ISI: 000260553100004OAI: oai:DiVA.org:liu-86923DiVA: diva2:583288