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Caspases: more than just killers?
Department of Immunology and Cell Biology, University of Münster, Münster, Germany.ORCID iD: 0000-0001-9518-1411
Dept of Immunology and Cell Biology, University of Münster, D-48149 Münster, Germany.
Dept of Immunology and Cell Biology, University of Münster, D-48149 Münster, Germany.
Dept of Immunology and Cell Biology, University of Münster, D-48149 Münster, Germany.
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2001 (English)In: Trends in immunology, ISSN 1471-4906, E-ISSN 1471-4981, Vol. 22, no 1, 31-34 p.Article, review/survey (Refereed) Published
Abstract [en]

Proteases of the caspase family constitute the central executioners of apoptosis, Several recent observations suggest that caspases and apoptosis-regulatory molecules exert important functions beyond that of cell death, including the control of T-cell proliferation and cell-cycle progression. Here, Los and colleagues propose a model that directly connects cell suicide mechanisms to the regulation of cell-cycle progression.

Place, publisher, year, edition, pages
Elsevier, 2001. Vol. 22, no 1, 31-34 p.
Keyword [en]
activation, Apoptosis, Bcl-2, cycle entry, death, division, fadd/mort1, inhibitor, Mice, t-cell proliferation
National Category
Biochemistry and Molecular Biology Cell Biology
Identifiers
URN: urn:nbn:se:liu:diva-87018DOI: 10.1016/S1471-4906(00)01814-7ISI: 000169935400011PubMedID: 1286689OAI: oai:DiVA.org:liu-87018DiVA: diva2:584248
Available from: 2013-01-08 Created: 2013-01-08 Last updated: 2017-12-06

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Los, Marek Jan

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