Development of the model for the optical monitoring of urea in spent dialysate
2012 (English)In: Electronics Conference (BEC), 2012, 2012, 179-182 p.Conference paper (Refereed)
The aim of the study was to develop a mathematical model suitable for the estimation of urea concentration removed during dialysis through UV-absorbance. 29 haemodialysis patients on chronic three-times-a-week haemodialysis were studied in 6 separate studies. Double-beam spectrophotometer was used for the determination of UV-absorbance in the collected spent dialysate samples. A single wavelength (SW) and a multi-wavelength (MW) model were developed using stepwise regression utilizing urea values from the laboratory as the dependent parameter. For SW model R2 was 0.656 (calibration set) and 0.729 (validation set), for MW model R2 was 0.696 and 0.764, respectively. In summary, the urea concentration removed during dialysis can be estimated with UV-absorbance technique.
Place, publisher, year, edition, pages
2012. 179-182 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-87611DOI: 10.1109/BEC.2012.6376846ISBN: 978-1-4673-2775-6OAI: oai:DiVA.org:liu-87611DiVA: diva2:589741
13th Biennial Baltic Electronics Conference (BEC 2012), 3-5 October 2012, Tallin, Estonia