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Development of the model for the optical monitoring of urea in spent dialysate
Tallinn University of Technology, Estonia .
Tallinn University of Technology, Estonia .
Linköping University, Department of Medical and Health Sciences, Internal Medicine. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Heart and Medicine Centre, Department of Nephrology UHL.
Tallinn University of Technology, Estonia .
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2012 (English)In: Electronics Conference (BEC), 2012, 2012, 179-182 p.Conference paper (Refereed)
Abstract [en]

The aim of the study was to develop a mathematical model suitable for the estimation of urea concentration removed during dialysis through UV-absorbance. 29 haemodialysis patients on chronic three-times-a-week haemodialysis were studied in 6 separate studies. Double-beam spectrophotometer was used for the determination of UV-absorbance in the collected spent dialysate samples. A single wavelength (SW) and a multi-wavelength (MW) model were developed using stepwise regression utilizing urea values from the laboratory as the dependent parameter. For SW model R2 was 0.656 (calibration set) and 0.729 (validation set), for MW model R2 was 0.696 and 0.764, respectively. In summary, the urea concentration removed during dialysis can be estimated with UV-absorbance technique.

Place, publisher, year, edition, pages
2012. 179-182 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-87611DOI: 10.1109/BEC.2012.6376846ISBN: 978-1-4673-2775-6OAI: diva2:589741
13th Biennial Baltic Electronics Conference (BEC 2012), 3-5 October 2012, Tallin, Estonia
Available from: 2013-01-19 Created: 2013-01-19 Last updated: 2013-02-04

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Fridolin, IvoUhlin, Fredrik
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Internal MedicineFaculty of Health SciencesDepartment of Nephrology UHL
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