Incidence, prevalence and clinical characteristics of Behcets disease in southern Sweden
2013 (English)In: Rheumatology, ISSN 1462-0324, E-ISSN 1462-0332, Vol. 52, no 2, 304-310 p.Article in journal (Refereed) Published
Objective. To study the incidence, prevalence and clinical characteristics of Behc, ets disease (BD) in a defined population in southern Sweden. less thanbrgreater than less thanbrgreater thanMethods. The study area consists of three health-care districts with an adult population (andgt;= 15 years) of 809 317 on 1 January 2011 (25% of non-Swedish ancestry), situated in Skane, the southernmost county in Sweden. Patients were identified using clinical registries in all the five hospitals within the study area. Only patients fulfilling the International Study Group criteria for diagnosis of BD were included. less thanbrgreater than less thanbrgreater thanResults. Forty patients (13 women) fulfilling the diagnosis criteria for BD (70% of non-Swedish ancestry) were identified. The point prevalence of BD on 1 January 2011 was 4.9/100 000 adults (95% CI 3.4, 6.5) and was higher among the population of non-Swedish ancestry (13.6 vs 2.0/100 000, Pandlt;0.001), and higher among men (6.8 vs 3.2/100 000, P=0.019). There were 20 incident cases (diagnosed in Sweden between 1997 and 2010). The annual incidence rate was 0.2/100 000 adults (95% CI 0.1, 0.3) and was higher among the population of non-Swedish ancestry (0.6 vs 0.1/100 000, Pandlt;0.001). The incidence was 0.3/100 000 adults in men and 0.1/100 000 in women, P = 0.143. During the course of the disease, 100% of the patients developed oral ulceration, 80% genital ulcers, 88% skin lesions, 53% eye disease, 40% arthritis/arthralgia and 20% venous thrombosis. less thanbrgreater than less thanbrgreater thanConclusion. The prevalence of BD is higher in Sweden than previously reported, mainly due to immigration. The incidence of BD remains elevated for immigrants from high-prevalence regions even long after settling in Sweden.
Place, publisher, year, edition, pages
Oxford University Press (OUP): Policy B , 2013. Vol. 52, no 2, 304-310 p.
incidence, prevalence, Behcets disease, population-based study, epidemiology
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-89510DOI: 10.1093/rheumatology/kes249ISI: 000314054800013OAI: oai:DiVA.org:liu-89510DiVA: diva2:608380
Funding Agencies|Swedish Research Council|64X.09487-181|Faculty of Medicine, Lund University||Thelma Zoegas Foundation for Medical Research in Helsingborg, Sweden||Swedish Rheumatism Association (Reumatikerforbundet)||2013-02-272013-02-262014-02-28