Reproductive patterns among twins: a Swedish register study of men and women born 1973-1983
2013 (English)In: BMC Pregnancy and Childbirth, ISSN 1471-2393, Vol. 13Article in journal (Refereed) Published
During the last decades there has been a steady increase of twin births. A combination of improved medical treatment of preterm and small-for-gestational age children has contributed to a higher number of surviving twins. Prematurity is known to affect reproduction in a negative way. Few studies have focused on the potential effect twinning may have on future reproduction. Thus, the aim of this study was to investigate the effect of being born a twin compared to being born a singleton have on future reproduction.
In a national population-based register study, all individuals born between 1973–1983 who were alive and living in Sweden at 13 years of age (n = 1 016 908) constituted the sample. Data on each study subject’s own birth as well as the birth of their first offspring, and parental socio-demographic factors were collected from Swedish population based registers. Hazard ratios and corresponding 95% CI was calculated using Cox proportional hazards model.
Twins, both men and women, had a reduced likelihood of reproducing compared to singletons (women: HR = 0.89, 95% CI = 0.86-0.93; men: HR = 0.92, 95% CI = 0.87-0.97). This difference in birth rates can only partly be explained by diverging birth characteristics. Amongst men and women born very preterm, twins had an increased likelihood of reproducing compared to singletons (women: HR = 1.25, 95% CI = 1.02-1.62; men: HR = 1.34, 95% CI = 1.01-1.78).
Twins have lower reproduction rates compared to singletons, which only to a certain degree can be explained by diverging birth characteristics.
Place, publisher, year, edition, pages
2013. Vol. 13
Twin, Singleton, Reproduction rate, Birth characteristics
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-89750DOI: 10.1186/1471-2393-13-6ISI: 000314290200001OAI: oai:DiVA.org:liu-89750DiVA: diva2:609360
Funding Agencies|Medical Research Council of Southeast Sweden||2013-03-052013-03-052015-09-11