Ruling out cardiac failure: Cost-benefit analysis of a sequential testing strategy with NT-proBNP before echocardiography
2013 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 118, no 2, 75-79 p.Article in journal (Refereed) Published
Objectives. To estimate the possible economic benefit of a sequential testing strategy with NT-proBNP to reduce the number of echocardiographies.
Methods. Retrospective study in a third-party payer perspective. The costs were calculated from three Swedish counties: Blekinge, Östergötland, and Uppland. Two cut-off levels of NT-proBNP were used: 400 and 300 pg/mL. The cost-effectiveness of the testing strategy was estimated through the short-term cost avoidance and reduction in demand for echocardiographies.
Results. The estimated costs for NT-proBNP tests and echocardiographies per county were reduced by 33%–36% with the 400 pg/mL cut-off and by 28%–29% with the 300 pg/mL cut-off. This corresponded to a yearly cost reduction of approximately €2–5 million per million inhabitants in these counties.
Conclusion. The use of NT-proBNP as a screening test could substantially reduce the number of echocardiographies in the diagnostic work-up of patients with suspected cardiac failure, as well as the associated costs.
Place, publisher, year, edition, pages
Informa Healthcare, 2013. Vol. 118, no 2, 75-79 p.
Cost, echocardiography, health economics, heart failure, laboratory test, NT-proBNP
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-89968DOI: 10.3109/03009734.2012.751471ISI: 000317486000002PubMedID: 23230860OAI: oai:DiVA.org:liu-89968DiVA: diva2:610607